This would be extremely interesting for portraits or even action, as I love to play with DoF to suit my subjects. I see so much potential, combined with good control (possibly AI supported). Stuff like 'keep the face and ball/sword/torch/etc in focus, blur the rest'. There is so much creative potential by having fine/quick control over the plan of focus.
I hope the aperture is not too closed, the brighter the better for me. Like f2 and below is welcome for portrait models (ex 50mm), even if size/weight/price make it go above the 85 f1.2 or 28-70 f2.
Once they get out an RF 200 f2 (or hopefully something like a 100-200 f2 IS 1.4x or 135-200 1.8 or the like, I'll buy whatever they offer anyway, the EF 200 f2 is that good), this AF TS-E would be my highest-hopped for lens, and a solid reason to stay with Canon.