I have both, Sigma 150-600 C and RF 100-400."...the lower cost option".
RF 100-400 costs even less, and in many scenarios will give you more keepers.
The weight, size and minimum focus distance are of course an advantage of the RF 100-400.
But there is a big difference in reach between 600mm and 400mm.
And the sigma 150-600 C has a aperture of f5.6 up to 387mm
So if Sigma launched an RF version of the 150-600 with fairly well functioning autofocus (the EF version works really bad when enabling eye detect AF on RF cameras.), I would not hesitate to replace my EF 150-600 C, RF 100-400 and RF 800 f11 for this lens instead.
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