Hey Neuro,
When you coming to SF?
I used my lowepro protactic. BP 450 III in Alaska this year. Carried one body, RF trinity and RF 100-500. Plus, batteries, cards, charger, 14-in laptop... Fits under your seat or an overhead, no problem. I don't check camera gear. I'm happy to arrive without clothes, but I'm not happy to arrive without my gear.
My dad's a retired pilot. My mom's retired flight attendant. I'd rather not check my camera gear.